Objectives : Evaluate the ability of predicting the ratings of perceived exertion from the external load variables in professional soccer players through a chronological perspective (i.e., past features values are considered additional features) through machine learning models by considering the playing position. Design: Prospective cohort study. Methods: Thirty-eight elite soccer players aged 19-27 years were observed during 151 training sessions, 44 matches across a full season. External load variables (58 derived from Global Positioning System and 30 from accelerometers) and the internal load derived from ratings of perceived exertion were collected for each player and each session and match. Machine learning models (linear regression, K-NN, decision trees, random forest, elastic net regression, XGBoost) were compared and interpreted in order to deepen the relationship between external load variables and ratings of perceived exertion according to the player position in a predictive perspective. Results : Application of the machine learning models on the dataset provided enough predictive power to reduce the Root Mean Squared Error of 60 % from dummy predictions. The most accurate models (Root Mean Squared Error ≈ 1.1 for random forest and = 1 for XGBoost) highlighted a memory effect in subsequent ratings of perceived exertion values. Past ratings of perceived exertion values over one month were the strongest predicting factors of ratings of perceived exertion as compared to various external load indicators. Conclusions : The tree-based machine learning models showed statistically significant predictive ability, indicating valuable information for understanding the training load responses based on ratings of perceived exertion changes.