When mobile field hospitals are deployed in response to a disaster, they may sometimes face unprecedented challenges that require collaboration either with other mobile field hospitals or with existing regional hospitals to maintain continuity of care for the impacted populations. This article explores the pivotal role of enhancing healthcare team collaboration to ensure seamless care continuity during disaster response in an austere disaster-stricken environment. To improve patient outcomes during disasters, this study aims to investigate the barriers to care continuity in disaster response and highlight frameworks that can enhance healthcare team collaboration during sudden onset of disasters. Several bibliographical databases, including Pub Med, Science Direct, Web of Science, and Google Scholar were utilized. Articles examined from the databases were focused on state-of-the-art healthcare collaboration frameworks. To shed light on the difficulties and the necessity of implementing a collaborative healthcare disaster response framework, a case study of an American mobile field hospital deployed during the 2010 Haiti earthquake was examined. The literature review highlighted several factors that are responsible for lack of coordination during disaster response especially in an austere setting like Haiti. The review further highlights some frameworks that have the potential to improve care continuity in such an environment. In the event of a disaster, especially in austere settings like Haiti where the usual coordination mechanisms with regional or local government is difficult, deployed mobile hospitals must find alternative frameworks to enable them to work in tandem among themselves and with the local hospitals to improve the affected population’s continuity of care. The five frameworks highlighted have the potential to facilitate care coordination and hence continuity of care in such settings.