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Why we use PEKK? Material’s characteristics and clinical results

Perrin Didier
Philippe Penot
  • Fonction : Auteur
Jacques Boulot
  • Fonction : Auteur


Introduction: PEKK is a semi-crystalline thermoplastics having high mechanical strength. From previous work, PEKK appears to provide good surface adhesion to support cell activity. Methods: We present the mechanical properties of OXPEKK® compared to bone: elasticity, wettability by tissue fluids, and design of devices allow us to obtain a mechanical behavior equivalent to its bone environment. We compare the surface conditions between the machined OXPEKK® and the sandblasted OXPEKK®. SEM observations and an AFM-microscopy study allowed us to compare the surface conditions of OXPEKK® implants before and after gamma-ray sterilization. The OXPEKK® implants are often used with MBCP™ bone substitute. MBCP™ is a biphasic synthetic bone graft substitute, osteoconductive thanks to its micro and macro porous structure. Soluble and resorbable, it promotes bone regrowth. Results: We present the results of an OXPEKK®-vs-PEEK rabbit implantation study and compare the osseointegration kinetics on both materials. We show the results of a clinical study (30 patients, 1-3 years follow-up): it demonstrates safety and effectiveness of the OXPEKK® medical device used with the MBCP™ substitute for the treatment of lumbar degenerative diseases regarding the lordosis recovering as well as the fusion rate. Finally, some long-term results of implantation of OXPEKK® cages on scoliosis cases are shown. Conclusion: OXPEKK® has mechanical characteristics comparable to human bone, good mechanical dynamic behavior, and its physical-chemical surface properties guarantee rapid osseointegration of implants. The radiolucency of OXPEKK® makes possible to visualize new bone regrowth, thanks to MBCP™ bone substitute which has a resorption rate similar to human bone.
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Dates et versions

hal-02510683 , version 1 (18-03-2020)


  • HAL Id : hal-02510683 , version 1


Max Nemoz-Gaillard, Perrin Didier, Philippe Penot, Jacques Boulot. Why we use PEKK? Material’s characteristics and clinical results. BIOSPINE 2019 - 7th International Congress on Biotechnologies for Spinal Surgery, Apr 2019, Rome, Italy. ⟨hal-02510683⟩
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